Clinical Presentation, Diagnosis and Treatment of Uterine Myomas

The aim of the paper was to consider the pathophysiological genesis of uterine myomas, especially diagnostic and therapeutic modalities, stressing the principles leading to rational decision-making process in individualizedmyoma management. The method presents a review of the recent literature on uterine myomas and synthesis of different authors' experiences. Uterinemyomas are themost common solid tumors in the female pelvic cavity. There is an increasing body of evidence of their genetic basis and of their growth related to genetic predisposition, hormonal influences and various growth factors. Diagnostic proceedings are numerous. There is a broad range of therapeutic options, including medicamentous, surgical and radiologic interventions. Most uterine myomas should be be serially monitored, observing thedevelopment of their symptomsorprogressive growth. In the last 50 years, highly sophisticated diagnostic and therapeutic technologies have been developed regarding uterine myomas. Nowadays, the available means allow us to be more flexible, with safe treatment modalities which canbe and must be adjusted to respective clinical situations.